As marijuana legalisation expands around the world, the plant’s cannabinoids appear to proliferate before the scientific community’s eyes. THCV Wholesale is no longer the greatest thing since sliced bread. It now has several siblings who compete for our attention. Today, we’ll teach you everything you need to know about THCV Isolate, THCB, and THCP, what makes them unique, and why we should keep a careful eye on their progress.
Although there are over 130 phytocannabinoids in the cannabis plant. Many of them have yet to be separated, therefore their effects remain unknown. With the exception of the THC molecule, which was discovered in Israel in the 1960s and whose function is best understood.
THCV Isolate, also known scientifically as -tetrahydrocannabinol, is a sedative-hypnotic chemical. That is responsible for the psychoactive properties of the cannabis plant, as well as the “high” of marijuana.
The THC achieves this by activating the CB1 and CB2 receptors of our endocannabinoid system. A neuromodulatory system responsible for maintaining our body’s equilibrium and regulating many of the functions that affect our health.
THC can exert analgesic and anti-inflammatory properties as a result of this interaction. Making it of tremendous interest to the medical cannabis business. Recreational cannabis users, on the other hand, have always preferred THC-rich strains.
All of this, however, could alter with the introduction of novel cannabinoids. Is THC the most intoxicating cannabinoid? Is it the one with the greatest therapeutic potential? Let us investigate.
THCV, the new medical cannabis star -tetrahydrocannabivarin (THCV). A minor component present in very low concentrations in comparison to the main cannabinoids, such as THC and CBD. According to a study published in the ‘Journal of Cannabis Research’ in 2020, this cannabinoid has more than one intriguing effect on our bodies:
– Reduces appetite and increases satiety.
– Stimulates metabolism. – Protects the nervous system. – Regulates blood sugar levels.
Unlike THC, which can increase hunger or create the well-known cannabis “munchies,” this cannabinoid has the potential to help people lose weight as well as treat obesity and type 2 diabetes.
All of these effects could be attributed to the ability of THCV Isolate to interact with our endocannabinoid system. THCV is a CB1 receptor antagonist, which means it binds to the receptor but does not activate it and inhibits it from being activated by other cannabinoids.
THC and THCV have a fairly similar chemical structure, with the key difference being two carbon atoms in the side chain that make the THCV Wholesale chain shorter.
This minor variation is enough to produce a slew of effects that are diametrically contrary to those of its elder brother, THC, which diminishes even its psychoactivity and elevates this phytocannabinoid to the status of “dietary herb.”
The THCV Wholesale is naturally found in extremely small amounts in marijuana, but Bona Voluntate has been able to offer our THCV Isolate strain to the market thanks to intensive breeding and stabilising efforts. A strain that has sufficient concentrations of this chemical (particularly, 7% THCV) enable you to evaluate its benefits.
THCP, the new psychoactive king
It’s no surprise that this cannabinoid is making waves in the cannabis market. Since its discovery in 2019 by a group of Italian scientists as a result of breakthroughs in mass spectrometry (a method used by scientists to determine the mass-to-charge ratio of molecules and identify chemicals). Its high psychotropic ability has grabbed the spotlight from its elder THC chain sibling.
-tetrahydrocannabiphorol (THCP) has the same chemical structure as THCV Isolate and THC, but its carbon side chain is longer. It can also bind to and activate the CB1 receptor, hence its activity is agonistic, like in the case of THC.
However, its affinity for the receptor appears to be 30 times higher than that of THC, implying that it has a greater ability to bind to this receptor. As a result, it is credited with a strong psychoactive potential that may outperform THC’s “high.”
This could be because cannabinoids’ ability to bind to the CB1 receptor is proportional to the length of their side chain. This notion had already been tested in the lab using synthetic cannabinoids with more than 5 carbons in their side chain. Prior to THCP, however, no natural phytocannabinoid with such a long chain (7 carbons) had been discovered.
The discovery of this novel cannabinoid could explain why some cultivars with low THC percentages have such strong psychoactive effects; thus, we may be disregarding their THCV Wholesale content.
This new phytocannabinoid’s medicinal properties are still being studied, but great things are expected of it. Currently, an Italian study found that THCP exerted the same analgesic effects in rats with half the amount of THC. Therefore curiosity in its therapeutic application would be totally justified.
THCB, the Emerging Cannabinoids’ Quiet Sibling
The discovery of THCB, or 9-tetrahydrocannabutol, can be attributed to the same research team that found THCP in 2019. Although its molecular structure is remarkably similar to that of THCP. Little is known about this substance because it has mostly gone ignored.
We currently know what happened at the University of Modena, where researchers isolated THCB. As well as another novel cannabinoid, CBDB, from a therapeutic type of Cannabis Sativa.
During the investigation, THCB binding capacity with the CB1 and CB2 receptors was determined. Which was found to be equivalent to THC binding capacity. Furthermore, its medicinal properties were evaluated in mice, with positive results showing analgesic and anti-inflammatory effects.
THCB’s most typical effects can also assist generate feelings of deep relaxation and tiredness. This shows that it could be beneficial for many people who have difficulty falling asleep. THCB is a promising chemical that may have increased appeal and wider use in the future. As sleeplessness is a common reason for marijuana use.
More research, however, will be required to determine all of the applications for this novel cannabinoid. The THCB is still in its early stages, with only one study establishing. Its existence and very briefly defining its properties.
Knowing the fundamental characteristics amongst the THCV Isolate members, it is reasonable to conclude that this is just the beginning. Cannabis legalisation in some nations has allowed for further research into this ancient plant, which continues to surprise us despite its age.